Aceclofenac: what it treats and how to use it safely

Aceclofenac is a common nonsteroidal anti-inflammatory drug (NSAID) that doctors prescribe for pain and inflammation — think osteoarthritis, rheumatoid arthritis, and low back pain. It’s a close relative of diclofenac and works by lowering chemicals in your body that cause pain and swelling. Before you take it, you should know the basics: why it's prescribed, how to take it, and the side effects to watch for.

How aceclofenac works and usual dosing

Aceclofenac blocks enzymes (COX) that make prostaglandins, the molecules that cause inflammation and pain. That’s why it helps stiffness and swelling in joints. The common adult dose is 100 mg twice a day with food to reduce stomach upset. Do not crush sustained‑release forms unless the label says so. Use the lowest effective dose for the shortest time that controls your symptoms.

If you have kidney or liver problems, or you’re older, your doctor may recommend a different dose or a different medicine. Don’t give aceclofenac to children unless a pediatrician prescribes and doses it specifically.

Side effects, warnings, and interactions

Most people tolerate aceclofenac, but side effects happen. The usual ones are stomach pain, heartburn, nausea, dizziness, and sometimes a skin rash. More serious risks include stomach bleeding, ulceration, liver enzyme changes, and kidney problems. If you notice black stools, severe belly pain, yellowing of skin/eyes, or sudden swelling, stop the drug and contact a doctor right away.

Aceclofenac can raise blood pressure and may increase the risk of heart problems when used long term, especially if you already have heart disease. Avoid it in late pregnancy — NSAIDs can harm the baby’s circulation and affect labor.

Drug interactions matter. Don’t combine aceclofenac with other NSAIDs (ibuprofen, naproxen) or aspirin for pain relief unless a doctor says it’s okay. It can interact with blood thinners (warfarin), ACE inhibitors and ARBs (blood pressure drugs), diuretics, lithium, and methotrexate. Tell your pharmacist about all medicines and supplements you take.

Practical tips: take aceclofenac with a meal, avoid alcohol while using it, and check with your doctor if you have a history of ulcers, heart disease, high blood pressure, kidney or liver issues. If pain doesn’t improve in a couple of weeks or side effects bother you, ask about alternatives like acetaminophen, physical therapy, or different NSAIDs.

Want more specifics? Ask your pharmacist for a patient leaflet or talk to your prescriber about how aceclofenac fits your health profile. Small changes—timing, food, monitoring—make a big difference in safety and comfort.